Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 10/20 | 0.55 |
| ▸ | PDE6C | P51160 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146830 | 0.77 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL29611957 | 0.77 | PDE5A (0.90) | PDE5APDE6C | |
| SCHEMBL6058528 | 0.72 | PDE5A (0.67) | PDE5APDE6CALDH1A1MAPTHSD17B10 | |
| SCHEMBL5964550 | 0.72 | PDE5A (0.70) | PDE5APDE6C | |
| SCHEMBL5990273 | 0.71 | PDE5A (0.50) | PDE5APDE6CALDH1A1MAPTKMT2A | |
| SCHEMBL147337 | 0.71 | PDE5A (1.00) | PDE5APDE6CALDH1A1KMT2AMEN1 | |
| SCHEMBL6367349 | 0.70 | PDE5A (0.84) | PDE5APDE6CPDE4B | |
| SCHEMBL1872915 | 0.70 | PDE5A (0.58) | PDE5APDE6CALDH1A1MAPTKMT2A | |
| SCHEMBL2567278 | 0.69 | PDE5A (0.70) | PDE5APDE6C | |
| SCHEMBL6634460 | 0.69 | PDE5A (0.55) | PDE5APDE6CALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153824-B2 | Inhibitors of phosphodiesterases in infertility | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-12-26 | — | — | US | disclosed |