Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698482 | 0.91 | ABL1 (0.43) | ABL1LIPE | |
| SCHEMBL6059070 | 0.82 | MCL1 (0.35) | MCL1ABL1PREP | |
| SCHEMBL12919164 | 0.75 | CA1 (0.46) | — | |
| SCHEMBL6860354 | 0.73 | ABL1 (0.42) | ABL1PREP | |
| Ammonia Solution, Strong SCHEMBL6697477 | 0.73 | ABL1 (0.41) | ABL1PREP | |
| SCHEMBL7259643 | 0.71 | KDM4E (0.37) | MCL1ABL1 | |
| SCHEMBL6058804 | 0.71 | PREP (0.46) | MCL1PREPTHRATHRB | |
| SCHEMBL4514274 | 0.70 | IDO1 (0.39) | ABL1 | |
| SCHEMBL13586884 | 0.70 | ELANE (0.39) | — | |
| SCHEMBL27358205 | 0.69 | AKR1C3 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-B1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | AVENTIS PHARMA SA (FR) | 2006-11-15 | — | — | EP | disclosed |