Hexane

Hexane

SCHEMBL6058673

CCCCCC.CN(C)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
AKR1B1 P15121 1/20 0.52
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX15 P16050 1/20 0.50
PDE4A P27815 1/20 0.50
PDE3A Q14432 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecane SCHEMBL8843443 0.97 GPR84 (0.55) ALDH1A1AKR1B1GPR84PPARGPPARD
Nonane SCHEMBL9503204 0.97 GPR84 (0.55) ALDH1A1AKR1B1GPR84PPARGPPARD
Decane SCHEMBL4634451 0.97 GPR84 (0.55) ALDH1A1AKR1B1GPR84PPARGPPARD
Octane SCHEMBL4633409 0.97 GPR84 (0.55) ALDH1A1AKR1B1GPR84PPARGPPARD
Hexanoate SCHEMBL28986099 0.87 AKR1B1 (0.76) ALDH1A1AKR1B1GPR84PPARGPPARD
Tetrabuthylammonium SCHEMBL28282438 0.87 SLC22A1 (0.57) ALDH1A1AKR1B1GPR84PPARGPPARD
Valeric Acid SCHEMBL28986130 0.84 AKR1B1 (0.64) ALDH1A1AKR1B1GPR84PPARGPPARD
Dimethylcarbate SCHEMBL28650000 0.84 KDM5A (0.48) ALDH1A1AKR1B1
Dimethylcarbate SCHEMBL3695848 0.83
Hexane SCHEMBL11414372 0.81 ALDH1A1 (0.55) ALDH1A1AKR1B1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453899-B1 Use of alkyl carboxylic acid dimethyl amides for inhibiting crystallisation BAYER AG (DE) 1993-12-29 EP claimed
EP-0453899-A1 Use of alkyl carboxylic acid dimethyl amides for inhibiting crystallisation BAYER AG (DE) 1991-10-30 EP claimed
EP-1379137-B1 USE OF FATTY ALCOHOL ETHOXYLATES AS PENETRATION PROMOTERS BAYER CROPSCIENCE AG (DE) 2006-08-16 EP disclosed
EP-1379137-A2 USE OF FATTY ALCOHOL ETHOXYLATES AS PENETRATION PROMOTERS Bayer CropScience AG (DE) 2004-01-14 EP disclosed
WO-2002098230-A2 USE OF FATTY ALCOHOL ETHOXYLATES AS PENETRATION PROMOTERS BAYER CROPSCIENCE AG (DE) 2002-12-12 WO disclosed
EP-0757891-A2 Solid formulations BAYER AG (DE) 1997-02-12 EP disclosed
WO-1995013702-A1 USE OF PHOSPHONIC ACID ESTERS AS CRYSTALLIZATION INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1995-05-26 WO disclosed
EP-0453899-B1 Use of alkyl carboxylic acid dimethyl amides for inhibiting crystallisation BAYER AG (DE) 1993-12-29 EP disclosed
EP-0453922-B1 USE OF COPPER SALTS FOR INHIBITING CRYSTALLISATION BAYER AG (DE) 1993-07-28 EP disclosed
EP-0473003-A2 Solidformulations BAYER AG (DE) 1992-03-04 EP disclosed
EP-0453899-A1 Use of alkyl carboxylic acid dimethyl amides for inhibiting crystallisation BAYER AG (DE) 1991-10-30 EP disclosed
EP-0453922-A1 Use of copper salts for inhibiting crystallisation BAYER AG (DE) 1991-10-30 EP disclosed