Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453416 | 0.82 | ACHE (0.42) | ACHEHSP90AB1L3MBTL1 | |
| SCHEMBL6058439 | 0.77 | ACHE (0.40) | ACHEHSP90AB1GABRA1GABRB2FABP3 | |
| SCHEMBL5952293 | 0.75 | ACHE (0.49) | ACHEHSP90AB1GABRA1GABRB2 | |
| SCHEMBL5951805 | 0.71 | ACHE (0.45) | ACHE | |
| SCHEMBL6058839 | 0.71 | ACHE (0.53) | ACHEL3MBTL1 | |
| SCHEMBL15822170 | 0.68 | ACHE (0.62) | ACHEL3MBTL1 | |
| SCHEMBL8810592 | 0.68 | FABP3 (0.38) | HSP90AB1GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL18772409 | 0.67 | ACHE (0.58) | ACHEHSP90AB1 | |
| SCHEMBL15931778 | 0.67 | ACHE (0.51) | ACHEHSP90AB1 | |
| SCHEMBL4202516 | 0.66 | ACHE (0.45) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545304-B1 | Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts | BASELL POLYOLEFINE GMBH (DE) | 2002-06-19 | — | — | EP | claimed |
| EP-0770587-B1 | Process for the production of an indene compound and its use for the production of a metallocene catalyst | BASELL POLYOLEFINE GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-0545304-B1 | Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts | BASELL POLYOLEFINE GMBH (DE) | 2002-06-19 | — | — | EP | disclosed |
| US-6051522-A | Catalyst which can be used for the preparation of olefins during polymerization | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |
| US-5929264-A | Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts | TARGOR GMBH (DE) | 1999-07-27 | — | — | US | disclosed |
| US-5852142-A | Process for the preparation of an olefin polymer | TARGOR GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5840948-A | Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0705281-B1 | SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF | EXXON CHEMICAL PATENTS INC (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0545303-B1 | Process for preparing high molecular weight polyolefins | HOECHST AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| EP-0770587-A2 | Process for the production of an indene compound and its use for the production of a metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0587107-B1 | Process for the preparation of substituted indanones | HOECHST AG (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0568879-B1 | Process for the preparation of substituted indanones and their use | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5374752-A | Catalyst system containing metallocene | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | disclosed |
| US-5360936-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| US-5328969-A | Cocatalyst of an aluminoxane and metallocene | HOECHST AKTIENGELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5329050-A | Process for the preparation of substituted indanones, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0587107-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0568879-A1 | Process for the preparation of substituted indanones and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-10 | — | — | EP | disclosed |
| EP-0545303-A1 | Process for preparing high molecular weight polyolefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0545304-A1 | Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | disclosed |