Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL3291430 | 0.88 | HSD17B10 (0.48) | HSD17B10MAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL9636848 | 0.87 | — | — | |
| SCHEMBL6880828 | 0.87 | — | — | |
| SCHEMBL15902740 | 0.87 | HSD17B10 (0.62) | HSD17B10MAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL15671 | 0.87 | — | — | |
| Acetic Acid SCHEMBL2791218 | 0.85 | HSD17B10 (0.48) | HSD17B10MAPK1MAPTTSHRALDH1A1 | |
| Water SCHEMBL27656190 | 0.85 | — | — | |
| Ethyl Acetate SCHEMBL152186 | 0.85 | ALDH1A1 (0.58) | HSD17B10MAPTTSHRALDH1A1TDP1 | |
| Ether SCHEMBL7090487 | 0.85 | HSD17B10 (0.45) | HSD17B10MAPK1MAPTTSHRALDH1A1 | |
| Methyl Isobutyl Ketone SCHEMBL139429 | 0.83 | ALDH1A1 (0.56) | HSD17B10MAPK1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105759568-A | Positive Photosensitive Siloxane Resin Composition And Display Device Formed Using The Same | 三星显示有限公司 | 2016-07-13 | — | — | CN | claimed |
| US-20050026260-A1 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | RESNICK SOL M (US) | 2005-02-03 | — | — | US | claimed |
| US-11904282-B2 | Method of controlling structure of defects in chabazite zeolite membranes through low temperature heat treatment | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2024-02-20 | — | — | US | disclosed |
| US-20210286269-A1 | METHOD FOR FORMING SEMICONDUCTOR STRUCTURE | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2021-09-16 | — | — | US | disclosed |
| US-20210213393-A1 | METHOD OF CONTROLLING STRUCTURE OF DEFECTS IN CHABAZITE ZEOLITE MEMBRANES THROUGH LOW TEMPERATURE HEAT TREATMENT | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2021-07-15 | — | — | US | disclosed |
| EP-3159737-B1 | LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT | NISSAN CHEMICAL CORP (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-11009796-B2 | Method for forming semiconductor structure | TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) | 2021-05-18 | — | — | US | disclosed |
| WO-2020138189-A1 | FILM FORMING COMPOSITION | 日産化学株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020085508-A1 | FILM-FORMING COMPOSITION | 日産化学株式会社 | 2020-04-30 | — | — | WO | disclosed |
| CN-110387138-A | Methylidyne compound, colored resin composition, coloring cured film and its manufacturing method, colored filter, printing ink and application thereof | 日本化药株式会社 | 2019-10-29 | — | — | CN | disclosed |
| CN-109937225-A | For solidifying the non-tin catalyst of the polymer containing alkoxysilyl | 莫门蒂夫性能材料股份有限公司 | 2019-06-25 | — | — | CN | disclosed |
| WO-2003083126-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030077461-A1 | Stacked film, insulating film and substrate for semiconductor | JSR CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1298176-A2 | Stacked film insulating film and substrate for semiconductor | JSR Corporation (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20030059628-A1 | Stacked film, method for the formation of stacked film, insulating film, and substrate for semiconductor | JSR CORPORATION (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1295924-A2 | Stacked film, method for the formation of stacked film, insulating film, and substrate for semiconductor | JSR Corporation (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5578377-A | ANTIREFLECTIVE FILM | ASAHI GLASS COMPANY LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0222888-A4 | COMPOSITION AND METHOD FOR INHIBITING THE CURE OF CYANOACRYLATE ADHESIVES AND CURE INHIBTED CYANOACRYLATE ADHESIVE COMPOSITIONS. | LAZAR WARREN GREGORY | 1989-02-16 | — | — | EP | disclosed |
| EP-0222888-A1 | COMPOSITION AND METHOD FOR INHIBITING THE CURE OF CYANOACRYLATE ADHESIVES AND CURE INHIBTED CYANOACRYLATE ADHESIVE COMPOSITIONS | LAZAR, Warren Gregory (US) | 1987-05-27 | — | — | EP | disclosed |
| WO-1986006738-A1 | COMPOSITION AND METHOD FOR INHIBITING THE CURE OF CYANOACRYLATE ADHESIVES AND CURE INHIBTED CYANOACRYLATE ADHESIVE COMPOSITIONS | LAZAR WARREN GREGORY | 1986-11-20 | — | — | WO | disclosed |