SCHEMBL6059211

SCHEMBL6059211

CCCCCc1ccc(-c2ccc3cc4ccccc4cc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.49
RARB P10826 8/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 1/20 0.49
RARA P10276 2/20 0.48
BCHE P06276 2/20 0.48
RARG P13631 1/20 0.48
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
MTOR P42345 1/20 0.47
KMT2A Q03164 1/20 0.47
HRH3 Q9Y5N1 1/20 0.45
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25177373 0.93 HSD17B10 (0.56) RARBHSD17B10TSHRRARARARG
SCHEMBL25171263 0.93 HSD17B10 (0.56) RARBHSD17B10TSHRRARARARG
SCHEMBL25177517 0.93 HSD17B10 (0.56) RARBHSD17B10TSHRRARARARG
SCHEMBL20814569 0.89 HSD11B1 (0.49) HSD11B1RARBHSD17B10TSHRRARA
SCHEMBL20814645 0.89 HSD11B1 (0.49) HSD11B1RARBHSD17B10TSHRRARA
SCHEMBL20814576 0.89 HSD11B1 (0.49) HSD11B1RARBHSD17B10TSHRRARA
SCHEMBL20814575 0.89 HSD11B1 (0.49) HSD11B1RARBHSD17B10TSHRRARA
SCHEMBL20814553 0.89 HSD11B1 (0.49) HSD11B1RARBHSD17B10TSHRRARA
SCHEMBL28156832 0.88 HSD17B10 (0.57) RARBHSD17B10TSHRRARARARG
Hydrogen Sulfide SCHEMBL20335338 0.87 SIGMAR1 (0.51) HSD11B1RARBHSD17B10TSHRRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268588-A4 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER SAMSUNG ATOFINA CO LTD (KR) 2006-03-29 EP disclosed
EP-1268588-A1 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER Samsung General Chemicals Co., Ltd. (KR) 2003-01-02 EP disclosed
WO-2001046282-A1 ETHYLENE-AROMATIC VINYL COMPOUND-VINYL NORBONENE TERPOLYMER SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-06-28 WO disclosed