SCHEMBL605923

SCHEMBL605923

Cn1c(N)nc2c3cccnc3ccc21

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 12/20 0.50
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
HTT P42858 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
HIF1A Q16665 1/20 0.45
CYP3A4 P08684 1/20 0.42
TLR7 Q9NYK1 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL17583545 0.98 PDE10A (0.49) PDE10ALMNAMAPTKDM4EMEN1
Bromide SCHEMBL13822734 0.97 PDE10A (0.48) PDE10ALMNAMAPTKDM4EMEN1
SCHEMBL12068237 0.83 PDE10A (0.54) PDE10ALMNAMAPTKDM4ECYP3A4
SCHEMBL28454970 0.80 PDE10A (0.43) PDE10AMAPTKDM4EMEN1HTT
SCHEMBL10345238 0.80 PDE10A (0.72) PDE10ALMNAMAPTKDM4ETLR7
SCHEMBL83775 0.79 PDE10A (0.48) PDE10ALMNAMAPTKDM4ECYP3A4
SCHEMBL15033539 0.79 PDE10A (0.48) PDE10ALMNAMAPTKDM4ECYP3A4
SCHEMBL4952115 0.78 PDE10A (0.47) PDE10ALMNAMAPTKDM4EMEN1
SCHEMBL10277184 0.78 PDE10A (0.50) PDE10ALMNAMAPTKDM4EMEN1
SCHEMBL10309409 0.78 PDE10A (0.59) PDE10ALMNAMAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117757091-A Magnetic metal organic framework material and preparation method and application thereof 北京工商大学 2024-03-26 CN claimed
EP-3694343-B1 CIGARETTE ROLLING PAPERS FORMED FROM KOMBUCHA BIOFILMS MOSHASHA SHAUN (US) 2023-11-22 EP claimed
CN-112881568-B Method for simultaneously measuring multiple associated harmful substances in food thermal processing 大连工业大学 2023-11-17 CN claimed
CN-116381087-A Method for simultaneously detecting 17 kinds of hot processing hazardous substances in class 4 and application thereof 中国农业大学 2023-07-04 CN claimed
CN-114403373-A Method for reducing heterocyclic amines in thermally processed meat patties and application of resveratrol 广东百味佳味业科技股份有限公司 2022-04-29 CN claimed
CN-113662127-A Method for reducing heterocyclic amine content in baked yellow croaker by using essential oil 大连工业大学 2021-11-19 CN claimed
US-11033050-B2 Cigarette rolling papers formed from kombucha biofilms KOMBUCHA BIOMATERIALS LLC (US) 2021-06-15 US claimed
CN-111999401-A Method for detecting amine hazardous substances in food 广东石油化工学院 2020-11-27 CN claimed
EP-3694343-A1 CIGARETTE ROLLING PAPERS FORMED FROM KOMBUCHA BIOFILMS Moshasha, Shaun (US) 2020-08-19 EP claimed
US-20190174815-A1 CIGARETTE ROLLING PAPERS FORMED FROM KOMBUCHA BIOFILMS KOMBUCHA BIOMATERIALS LLC 2019-06-13 US claimed
WO-2019075422-A1 CIGARETTE ROLLING PAPERS FORMED FROM KOMBUCHA BIOFILMS MOSHASHA SHAUN (US) 2019-04-18 WO claimed
JP-1169357-A None JP disclosed
CN-120009444-A Method for testing and analyzing heterocyclic amine compound in food 上海微谱检测认证有限公司 2025-05-16 CN disclosed
CN-114920892-B Magnetic heterocyclic amine molecularly imprinted composite material and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2025-03-28 CN disclosed
US-20250084398-A1 SYSTEMS FOR MODULATING DRUG METABOLISM BY CELLS, METHODS AND COMPOSITIONS THEREOF TROBIX BIO LTD (IL) 2025-03-13 US disclosed
JP-H01169357-A ANTIBODY AGAINST CARCINOGEN OTSUKA PHARMACEUT CO LTD 1989-07-04 JP disclosed
US-4777052-A PRETREATMENT WITH TRYPTOPHAL, BEFORE HEATING AMERICAN HEALTH FOUNDATION (US) 1988-10-11 US disclosed
US-4623638-A CHROMATOGRAPHY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-18 US disclosed
EP-0157549-A2 Silica gel linked to a phthalocyanine compound and a method for treating polycyclic organic substances therewith SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-09 EP disclosed
US-4460475-A Method for treatment of mutagens SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084398-A1 SYSTEMS FOR MODULATING DRUG METABOLISM BY CELLS, METHODS AND COMPOSITIONS THEREOF SHMT2, FPGS, GLS2 PDE10A 2845/4885LMNA 3193/4885MAPT 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.