Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546203 | 0.81 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL29798917 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL27737001 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL5546191 | 0.79 | ACHE (0.35) | ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL28233022 | 0.79 | NPC1 (0.41) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL26004981 | 0.78 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| Hydrogen Sulfide SCHEMBL28059716 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL1897895 | 0.75 | NPC1 (0.36) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL30524348 | 0.75 | NPC1 (0.46) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL7067289 | 0.75 | NPC1 (0.46) | NPC1RAB9AALDH1A1PLA2G1BNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058557-A1 | Bis-chelating ligand and use thereof in carbonylation processes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058557-A1 | Bis-chelating ligand and use thereof in carbonylation processes | CBR1, CBR3, AR | NPC1 4519/4885RAB9A 2327/4885ALDH1A1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.