Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546048 | 0.85 | DRD2 (0.45) | RAB9AMEN1MAPK1KMT2ADRD2 | |
| SCHEMBL27545973 | 0.78 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3HTR2CRAB9A | |
| SCHEMBL1628502 | 0.78 | SLC6A2 (0.51) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL6399792 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2D6 | |
| SCHEMBL3172248 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL18244743 | 0.76 | DRD2 (0.43) | MEN1MAPK1KMT2ADRD2CA12 | |
| SCHEMBL11140195 | 0.76 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL11140216 | 0.76 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL5584464 | 0.74 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL5584716 | 0.74 | HTR2C (0.69) | SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7145047-B2 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-12-05 | — | — | US | disclosed |
| US-20030136944-A1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030136944-A1 | Naphthalene derivative and liquid crystal composition comprising the same | NLK, NOTCH1, NOTCH4 | SLC6A4 2035/4885SLC6A2 1663/4885SLC6A3 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.