SCHEMBL6059433

SCHEMBL6059433

Cc1nc2ccccc2c(C#N)c1C#N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
KDM4E B2RXH2 3/20 0.68
GPR3 P46089 1/20 0.53
HSD17B10 Q99714 4/20 0.48
CYP1A2 P05177 3/20 0.48
HPGD P15428 2/20 0.48
NUDT1 P36639 1/20 0.48
PDE10A Q9Y233 1/20 0.43
KDM4A O75164 1/20 0.43
KDM5B Q9UGL1 1/20 0.43
ADORA2A P29274 3/20 0.42
ADORA1 P30542 2/20 0.42
ADRA2A P08913 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
ERN1 O75460 1/20 0.41
CASP3 P42574 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5249857 0.87 ALDH1A1 (0.66) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL3970610 0.87 ALDH1A1 (0.60) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL14438249 0.84 ALDH1A1 (0.56) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL7094514 0.82 ALDH1A1 (0.55) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL2001240 0.81 KDM4E (1.00) ALDH1A1KDM4EGPR3HSD17B10HPGD
SCHEMBL11208532 0.80 PDE10A (0.64) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL22345522 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL19169958 0.73 GPR3 (0.53) ALDH1A1KDM4EGPR3HSD17B10CYP1A2
SCHEMBL6253855 0.73 KDM4E (0.56) ALDH1A1KDM4EHSD17B10CYP1A2HPGD
SCHEMBL2639136 0.73 ALDH1A1 (0.56) ALDH1A1KDM4EGPR3HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197162-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-23 US disclosed
CN-107111257-B Electrophotographic photoreceptor 三菱化学株式会社 2021-05-18 CN disclosed
US-20190346779-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2019-11-14 US disclosed
US-9977354-B2 Coating liquid for electrophotographic photoreceptor production, electrophotographic photoreceptor, and image formation apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-22 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed
EP-0977089-B1 Electrophotographic photosensitive member and process for producing the same MITSUBISHI CHEM CORP (JP) 2006-05-10 EP disclosed
US-6337165-B1 FOR FORMING IMAGES, DURABILITY, STABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-08 US disclosed
US-20010019804-A1 Electrophotographic photosensitive member and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2001-09-06 US disclosed
US-6214506-B1 Electrophotographic photosensitive member and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2001-04-10 US disclosed
US-6197463-B1 USED IN PRINTER AND COPIERS; WEAR RESISTANCE; PRINTING RESISTANCE; DURABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 2001-03-06 US disclosed
EP-0977089-A1 Electrophotographic photosensitive member and process for producing the same Mitsubishi Chemical Corporation (JP) 2000-02-02 EP disclosed