Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161748 | 0.91 | LMNA (0.42) | LMNA | |
| SCHEMBL191906 | 0.89 | LMNA (0.39) | LMNATSHRTHRB | |
| SCHEMBL3362163 | 0.89 | LMNA (0.39) | LMNATSHRTHRB | |
| SCHEMBL191387 | 0.89 | LMNA (0.39) | LMNATSHRTHRB | |
| SCHEMBL191411 | 0.89 | LMNA (0.39) | LMNATSHRTHRB | |
| SCHEMBL14790662 | 0.87 | LMNA (0.42) | LMNA | |
| SCHEMBL2398969 | 0.87 | LMNA (0.36) | LMNATSHRTHRB | |
| Hexane SCHEMBL6049081 | 0.82 | LMNA (0.65) | LMNATSHRTHRBEPHX1 | |
| SCHEMBL35912 | 0.82 | LMNA (0.65) | LMNATSHRTHRBEPHX1 | |
| SCHEMBL377101 | 0.82 | LMNA (0.65) | LMNATSHRTHRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116280-A1 | Catalysts for polymerizing olefins and process for producing olefin polymer | IDEMITSU KOSAN CO., LTD. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1586589-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND PROCESS FOR PRODUCING OLEFIN POLYMER | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| EP-0790260-B1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5902765-A | MADE BY REACTING A MAGNESIUM DIHALIDE WITH TETRAHYDROFURAN, BUTYL ETHER OR DIETHYL ETHER AND TREATING THE SOLID SUBSTANCE WITH AN ELECTRON DONATIVE COMPOUND HAVING TWO OR MORE ALKOXY OR ESTER GROUPS, CONTACTING WITH TITANIUM; STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0790260-A1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |