Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452874 | 0.92 | LTA4H (0.56) | ESR2ESR1LTA4HLMNACYP1A2 | |
| SCHEMBL3418462 | 0.87 | ESR2 (0.59) | ESR2ESR1LTA4HLMNACYP1A2 | |
| SCHEMBL14218326 | 0.83 | ESR2 (0.54) | ESR2ESR1LTA4HLMNACYP1A2 | |
| SCHEMBL28279511 | 0.81 | LTA4H (0.64) | ESR2LTA4HMEN1KMT2AAPP | |
| SCHEMBL5633288 | 0.81 | APP (0.70) | ESR2ESR1LMNACYP1A2PTGS1 | |
| SCHEMBL2924048 | 0.81 | ALDH1A1 (0.58) | ESR2ESR1LTA4HAPPNR5A1 | |
| SCHEMBL22596639 | 0.81 | APP (0.70) | ESR2ESR1LMNACYP1A2PTGS1 | |
| SCHEMBL7448357 | 0.81 | LTA4H (0.76) | ESR2ESR1LTA4HNR5A1 | |
| SCHEMBL4354892 | 0.79 | APP (0.61) | ESR2ESR1LTA4HLMNACYP1A2 | |
| SCHEMBL17676808 | 0.78 | IDO1 (0.50) | ESR2ESR1LTA4HLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125951-B2 | Monomers containing at least one biaryl unit and polymers and derivatives prepared therefrom | SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040254327-A1 | Monomers containing at least one biaryl unit and polymers and derivatives prepared therefrom | SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY | 2004-12-16 | — | — | US | disclosed |
| WO-2004037879-A2 | MONOMERS CONTAINING AT LEAST ONE BIARYL UNIT AND POLYMERS AND DERIVATIVES PREPARED THEREFROM | SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY (US) | 2004-05-06 | — | — | WO | disclosed |