Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059676 | 1.00 | PTGS2 (0.49) | PTGS2NFE2L2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12535673 | 0.88 | ESR1 (0.42) | PTGS2ESR1TTRAPPNR1H4 | |
| SCHEMBL20064785 | 0.87 | NR1H4 (0.42) | ESR1TTRAPPNR1H4PTPN1 | |
| SCHEMBL1322382 | 0.86 | SNCA (0.56) | PTGS2CYP1A1CYP1A2CYP1B1TNFRSF1A | |
| SCHEMBL1322379 | 0.86 | SNCA (0.56) | PTGS2CYP1A1CYP1A2CYP1B1TNFRSF1A | |
| SCHEMBL23582834 | 0.85 | NR1H4 (0.43) | ESR1TTRAPPTNFRSF1ANR1H4 | |
| SCHEMBL1321266 | 0.85 | NR1H4 (0.41) | PTGS2ESR1TTRAPPNR1H4 | |
| SCHEMBL20158247 | 0.85 | TUBB1 (0.59) | NFE2L2ESR1BACE1TUBB1 | |
| SCHEMBL1321264 | 0.85 | NR1H4 (0.41) | PTGS2ESR1TTRAPPNR1H4 | |
| SCHEMBL30487467 | 0.85 | TUBB1 (0.59) | NFE2L2ESR1BACE1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735262-A1 | PROCESS FOR PREPARING CINNAMIC ACIDS AND ALKYL ESTERS THEREOF | Honeywell International, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005105728-A1 | PROCESS FOR PREPARING CINNAMIC ACIDS AND ALKYL ESTERS THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2005-11-10 | — | — | WO | disclosed |
| US-20050234261-A1 | Process for preparing cinnamic acids and alkyl esters thereof | HONEYWELL INTERNATIONAL INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234261-A1 | Process for preparing cinnamic acids and alkyl esters thereof | PCCA, LIPA, CA7 | PTGS2 2450/4885NFE2L2 2545/4885CYP1A1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.