SCHEMBL6060122

SCHEMBL6060122

CCc1ccc(C2(C(=O)O)CCCC2OC(C)=O)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 2/20 0.34
NPC1 O15118 4/20 0.33
RAB9A P51151 3/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060778 0.86 PTGS1 (0.37) ALDH1A1MEN1KMT2APOLBNPC1
SCHEMBL6060415 0.85 HTR2C (0.36) ALDH1A1MEN1KMT2APOLBSMN1; SMN2
SCHEMBL4813929 0.76 SLC22A1 (0.50) SMN1; SMN2OPRM1OPRD1OPRK1
SCHEMBL4809674 0.76 OPRM1 (0.44) MEN1KMT2ALMNAOPRM1OPRD1
SCHEMBL4813860 0.75 MEN1 (0.42) MEN1KMT2AHTT
SCHEMBL4814920 0.74 HTR2C (0.42) ALDH1A1SMN1; SMN2MAPTHPGDOPRM1
SCHEMBL4812898 0.71 SLC22A1 (0.38) ALDH1A1TSHROPRM1OPRD1OPRK1
SCHEMBL4808679 0.70 HTR2C (0.36) ALDH1A1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL10481760 0.69 AKR1C1 (0.41) MEN1KMT2ALMNAHTT
SCHEMBL6060835 0.67 CYP3A4 (0.33) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed