Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942280 | 0.91 | TSHR (0.66) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8942686 | 0.87 | TSHR (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methacrylic Acid SCHEMBL17627821 | 0.86 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Acrylic Acid SCHEMBL27710150 | 0.86 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Triethylene Glycol SCHEMBL28561866 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methoxymethane SCHEMBL2120311 | 0.85 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methoxymethane SCHEMBL9297841 | 0.85 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methoxymethane SCHEMBL7115643 | 0.85 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7889656 | 0.85 | TSHR (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Triethylene Glycol SCHEMBL2770781 | 0.85 | ALDH1A1 (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656116-A2 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY | Vista Scientific LLC (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005023181-A2 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY | VISTA SCIENTIFIC (US) | 2005-03-17 | — | — | WO | disclosed |