Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6060443

CCCCCCCCC(C)(CCCCCC)C(C)(Cl)Cc1ccccc1.N

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
MMP13 P45452 1/20 0.40
DNM1 Q05193 2/20 0.39
SLC6A2 P23975 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 1/20 0.38
PKM P14618 1/20 0.38
CSNK1E P49674 1/20 0.38
HTT P42858 2/20 0.37
KCNH2 Q12809 1/20 0.37
LMNA P02545 1/20 0.37
CYP2D6 P10635 1/20 0.37
SIGMAR1 Q99720 2/20 0.37
EBP Q15125 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL16427990 0.81 DNM1 (0.42) MMP1MMP9MMP13DNM1SLC6A2
Ammonia Solution, Strong SCHEMBL11273750 0.81 DNM1 (0.42) MMP1MMP9MMP13DNM1SLC6A2
Ammonia Solution, Strong SCHEMBL27433180 0.80 SLC6A2 (0.44) MMP1MMP9MMP13DNM1SLC6A2
Ammonia Solution, Strong SCHEMBL27641275 0.80 SLC6A2 (0.44) MMP1MMP9MMP13DNM1SLC6A2
SCHEMBL30603345 0.79 DNM1 (0.44) MMP1MMP9MMP13DNM1SLC6A2
SCHEMBL8057768 0.79 SLC6A2 (0.48) MMP1MMP9MMP13DNM1SLC6A2
Hydrochloric Acid SCHEMBL27579890 0.78 MMP1 (0.43) MMP1MMP9MMP13DNM1SLC6A2
Hydrochloric Acid SCHEMBL28091435 0.78 MMP1 (0.43) MMP1MMP9MMP13DNM1SLC6A2
Hydrochloric Acid SCHEMBL27789618 0.78 MMP1 (0.43) MMP1MMP9MMP13DNM1SLC6A2
Hydrochloric Acid SCHEMBL27696686 0.78 MMP1 (0.43) MMP1MMP9MMP13DNM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317576-B1 ANTIMICROBIAL POLYMERS UNIV CALIFORNIA (US) 2006-04-19 EP disclosed
EP-1317576-A2 STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-06-11 EP disclosed
WO-2002022923-A2 STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-03-21 WO disclosed