Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349497 | 0.80 | HDAC6 (0.36) | — | |
| SCHEMBL4436717 | 0.80 | HSD17B10 (0.33) | — | |
| SCHEMBL31269349 | 0.80 | HSD17B10 (0.33) | — | |
| SCHEMBL4520168 | 0.78 | HDAC6 (0.32) | — | |
| SCHEMBL1721310 | 0.78 | GDA (0.39) | — | |
| SCHEMBL7771667 | 0.78 | SLC2A1 (0.37) | — | |
| SCHEMBL19207482 | 0.74 | — | — | |
| SCHEMBL6046332 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL23409493 | 0.68 | HTT (0.39) | — | |
| SCHEMBL30842861 | 0.68 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660475-A1 | PYRIMIDYLPYRROLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014572-A1 | PYRIMIDYLPYRROLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2005-02-17 | — | — | WO | disclosed |