Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721310 | 0.82 | GDA (0.39) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL4520168 | 0.79 | HDAC6 (0.32) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL5349497 | 0.76 | HDAC6 (0.36) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL31269349 | 0.76 | HSD17B10 (0.33) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL4436717 | 0.76 | HSD17B10 (0.33) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7771667 | 0.75 | SLC2A1 (0.37) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7035226 | 0.73 | — | — | |
| SCHEMBL27486869 | 0.72 | ABL1 (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL6046334 | 0.71 | ALDH1A1 (0.55) | KDM4EALDH1A1 | |
| SCHEMBL6060475 | 0.71 | CTNNB1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161519-A1 | PURINES AND METHODS OF THEIR USE | Yumanity Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-2953470-A1 | 2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-12-16 | — | — | EP | disclosed |
| WO-2014123882-A1 | 2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20060199198-A1 | Polymorphic DNA fragments and uses thereof | SOLEXA, INC., | 2006-09-07 | — | — | US | disclosed |