Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 10/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072440 | 0.91 | AKT1 (0.36) | AKT1 | |
| SCHEMBL6060516 | 0.90 | AKT1 (0.40) | AKT1 | |
| SCHEMBL6061003 | 0.88 | AKT1 (0.42) | AKT1 | |
| SCHEMBL6060420 | 0.88 | AKT1 (0.42) | AKT1 | |
| SCHEMBL6060835 | 0.87 | CYP3A4 (0.33) | EP300HIF1ACREBBPACHECYP3A4 | |
| SCHEMBL4808452 | 0.86 | AKT1 (0.35) | ACHECYP3A4AKT1 | |
| SCHEMBL4810499 | 0.84 | AKT1 (0.45) | ACHEAKT1 | |
| SCHEMBL6060991 | 0.81 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL4814404 | 0.80 | AKT1 (0.36) | AKT1 | |
| SCHEMBL6060493 | 0.79 | HSD11B1 (0.36) | AKT1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006045246-A1 | CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2006-05-04 | — | — | WO | disclosed |