Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 12/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059867 | 0.91 | EGLN1 (0.52) | EGLN2EGLN1MCL1 | |
| SCHEMBL6061229 | 0.87 | EGLN1 (0.50) | EGLN2EGLN1MCL1 | |
| SCHEMBL6060874 | 0.84 | EGLN2 (0.52) | EGLN2EGLN1 | |
| SCHEMBL6060364 | 0.80 | EGLN1 (0.52) | EGLN2EGLN1 | |
| SCHEMBL6060396 | 0.78 | NPC1 (0.40) | EGLN1P4HTM | |
| SCHEMBL4958619 | 0.78 | EGLN1 (0.70) | EGLN2EGLN1 | |
| SCHEMBL6059798 | 0.78 | EGLN1 (0.48) | EGLN2EGLN1 | |
| SCHEMBL5315695 | 0.77 | EGLN1 (0.49) | EGLN2EGLN1 | |
| SCHEMBL6061166 | 0.76 | EGLN1 (0.58) | EGLN2EGLN1 | |
| SCHEMBL23929416 | 0.75 | EGLN1 (0.57) | EGLN2EGLN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN, INC. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004108681-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENOUS ERYTHROPOIETIN | FIBROGEN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |