Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | GPR3 | P46089 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806041 | 0.88 | PRCP (0.44) | HTR2APRCPCHRM1ADRA1ADRD3 | |
| SCHEMBL9662292 | 0.83 | HTR2A (0.48) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL1539788 | 0.81 | HTR2A (0.47) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL6027731 | 0.78 | HTR2A (0.48) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL6312576 | 0.78 | HTR2A (0.37) | HTR2APOLBMEN1KMT2AATM | |
| SCHEMBL8664813 | 0.77 | CYP2D6 (0.43) | HTR2APOLBMEN1KMT2APRCP | |
| SCHEMBL16590918 | 0.77 | HTR2A (0.42) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL17801651 | 0.77 | HTR2A (0.42) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL7769352 | 0.75 | HTR2A (0.45) | HTR2AGPR3POLBMEN1KMT2A | |
| SCHEMBL17022493 | 0.74 | HTR2A (0.44) | HTR2AGPR3POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365488-A1 | TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-11-16 | — | — | US | disclosed |
| EP-1298117-B1 | Method for preparing bromofluorenes | JFE CHEMICAL CORP (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-6858764-B2 | Method for preparing bromofluorenes | JFE CHEMICAL CORPORATION (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030065226-A1 | Method for preparing bromofluorenes | ADCHEMCO CORPORATION (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1298117-A2 | Method for preparing bromofluorenes | Adchemco Corporation (JP) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065226-A1 | Method for preparing bromofluorenes | FLNB, AFF2, BRPF1 | HTR2A 2043/4885GPR3 2714/4885POLB 181/4885 |
| US-20230365488-A1 | TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | FABP5, FABP1, FABP4 | HTR2A 1027/4885GPR3 291/4885POLB 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.