SCHEMBL6060798

SCHEMBL6060798

O=C(O)OCC(C(=O)O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
OR51E2 Q9H255 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PGD P52209 1/20 0.30
TSHR P16473 1/20 0.30
LMNA P02545 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18261395 0.77 TDP1 (0.46) TDP1TSHRLMNAALDH1A1RECQL
SCHEMBL17701379 0.77 PGK1 (0.50) PGK1PGK2OR51E2PGDTSHR
SCHEMBL11032771 0.76 FOLH1 (0.48) TDP1LMNA
SCHEMBL304089 0.75
SCHEMBL1492508 0.75 SLC22A6 (0.38) PGK1PGK2LMNAALDH1A1
SCHEMBL14366041 0.75 SLC1A5 (0.47) ALDH1A1
SCHEMBL10590102 0.75 GABRR1 (0.42) TSHR
SCHEMBL6820633 0.75 SLC1A5 (0.47) ALDH1A1
SCHEMBL8394092 0.73 PGK1 (0.35) PGK1PGK2OR51E2TDP1PGD
SCHEMBL319704 0.73 MAPT (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060177387-A1 Compositions comprising bone marrow cells, demineralized bone matrix and various site-reactive polymers for use in the induction of bone and cartilage formation SLAVIN SHIMON 2006-08-10 US disclosed
EP-1585556-A1 COMPOSITIONS COMPRISING BONE MARROW CELLS, DEMINERALIZED BONE MATRIX AND VARIOUS SITE-REACTIVE POLYMERS FOR USE IN THE INDUCTION OF BONE AND CARTILAGE FORMATION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2005-10-19 EP disclosed
WO-2004022120-A1 COMPOSITIONS COMPRISING BONE MARROW CELLS, DEMINERALIZED BONE MATRIX AND RTG POLYMERS FOR USE IN THE INDUCTION OF BONE AND CARTILAGE FORMATION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2004-03-18 WO disclosed
WO-2004022121-A1 COMPOSITIONS COMPRISING BONE MARROW CELLS, DEMINERALIZED BONE MATRIX AND VARIOUS SITE-REACTIVE POLYMERS FOR USE IN THE INDUCTION OF BONE AND CARTILAGE FORMATION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2004-03-18 WO disclosed