SCHEMBL1492508

SCHEMBL1492508

O=C(O)OCC(O)COC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
CYP1A2 P05177 2/20 0.34
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
ADRB2 P07550 2/20 0.33
ADRB1 P08588 2/20 0.33
ADRB3 P13945 2/20 0.33
DUSP3 P51452 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
P2RY10 O00398 3/20 0.33
GPR174 Q9BXC1 3/20 0.33
GPR34 Q9UPC5 2/20 0.33
LPAR6 P43657 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR4 Q99677 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44489 0.86
SCHEMBL2904699 0.86
SCHEMBL2905861 0.86
SCHEMBL6009745 0.84 LMNA (0.46) SLC22A6CYP1A2KDM4ELMNADUSP3
Ammonia Solution, Strong SCHEMBL29173217 0.84 LMNA (0.46) SLC22A6CYP1A2KDM4ELMNADUSP3
Bicarbonate SCHEMBL3335344 0.84 LMNA (0.46) SLC22A6CYP1A2KDM4ELMNADUSP3
SCHEMBL1525696 0.84
SCHEMBL5030996 0.84 LMNA (0.46) SLC22A6CYP1A2KDM4ELMNADUSP3
SCHEMBL11589388 0.82 THRB (0.42) SLC22A6KDM4ELMNADUSP3ALDH1A1
SCHEMBL8033641 0.82 LMNA (0.44) SLC22A6KDM4ELMNADUSP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
EP-3700749-B1 LAMINATE STRUCTURE FOR BIOCOMPATIBLE BARRIER PACKAGING RENOLIT SE (DE) 2023-01-11 EP claimed
US-11254108-B2 Laminate structure for biocompatible barrier packaging RENOLIT SE (DE) 2022-02-22 US claimed
CN-113597436-A Electrochemical production of polymers 何慧煌 2021-11-02 CN claimed
US-20200262186-A1 LAMINATE STRUCTURE FOR BIOCOMPATIBLE BARRIER PACKAGING RENOLIT SE (DE) 2020-08-20 US claimed
CN-111448064-A Layered structure for biocompatible barrier packaging 雷诺丽特欧洲公司 2020-07-24 CN claimed
EP-3476594-A1 LAMINATE STRUCTURE FOR BIOCOMPATIBLE BARRIER PACKAGING Renolit SE (DE) 2019-05-01 EP claimed
EP-2471559-B1 Antiviral method GOJO IND INC (US) 2014-11-26 EP claimed
WO-2014042391-A1 METHOD OF PREPARING POLYCARBONATE AND POLYCARBONATE PREPARED BY THE SAME SK INNOVATION CO.,LTD. (KR) 2014-03-20 WO claimed
US-20120172574-A1 Ring Opening Polymerisation of Cyclic Carbonates With Organic Catalyst Systems CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2012-07-05 US claimed
EP-2470585-A1 RING OPENING POLYMERISATION OF CYCLIC CARBONATES WITH ORGANIC CATALYST SYSTEMS Total Petrochemicals Research Feluy (BE) 2012-07-04 EP claimed
WO-2011023450-A1 RING OPENING POLYMERISATION OF CYCLIC CARBONATES WITH ORGANIC CATALYST SYSTEMS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-03-03 WO claimed
EP-2289971-A1 Ring opening polymerisation of cyclic carbonates with organic catalyst systems Total Petrochemicals Research Feluy (BE) 2011-03-02 EP claimed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO disclosed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US disclosed
US-10400064-B2 Glycerol-based polycarbonates TRUSTEES OF BOSTON UNIVERSITY (US) 2019-09-03 US disclosed
US-20120172574-A1 Ring Opening Polymerisation of Cyclic Carbonates With Organic Catalyst Systems CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2012-07-05 US disclosed
EP-2470585-A1 RING OPENING POLYMERISATION OF CYCLIC CARBONATES WITH ORGANIC CATALYST SYSTEMS Total Petrochemicals Research Feluy (BE) 2012-07-04 EP disclosed
WO-2011023450-A1 RING OPENING POLYMERISATION OF CYCLIC CARBONATES WITH ORGANIC CATALYST SYSTEMS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-03-03 WO disclosed
EP-2289971-A1 Ring opening polymerisation of cyclic carbonates with organic catalyst systems Total Petrochemicals Research Feluy (BE) 2011-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10400064-B2 Glycerol-based polycarbonates GK, AGPAT5, PC SLC22A6 403/4885CYP1A2 1666/4885KDM4E 1671/4885
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF MPO, SSB, SGMS2 SLC22A6 593/4885CYP1A2 3141/4885KDM4E 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.