Methacrylic Acid

Methacrylic Acid

SCHEMBL6060979

C=C(C)C(=O)O.C=C(CCCC)C(=O)OOC

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.40
CES1 P23141 2/20 0.35
CES2 O00748 1/20 0.34
ALDH1A1 P00352 4/20 0.33
THRB P10828 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
AKR1B1 P15121 1/20 0.32
TP53 P04637 1/20 0.32
PPARG P37231 6/20 0.31
PPARD Q03181 6/20 0.31
PPARA Q07869 6/20 0.31
GPR84 Q9NQS5 5/20 0.31
HDAC11 Q96DB2 5/20 0.31
TLR2 O60603 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
FABP4 P15090 2/20 0.31
PTPN1 P18031 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27985605 0.93 TSHR (0.38) TSHRCES1CES2ALDH1A1AKR1B1
SCHEMBL196996 0.91 CES1 (0.41) TSHRCES1CES2ALDH1A1AKR1B1
Methacrylic Acid SCHEMBL6060061 0.89 ALDH1A1 (0.35) TSHRCES1CES2ALDH1A1THRB
SCHEMBL10535382 0.88 ALDH1A1 (0.50) TSHRCES1CES2ALDH1A1THRB
Propionic Acid SCHEMBL27983610 0.88 AKR1B1 (0.38) TSHRCES1CES2ALDH1A1AKR1B1
Methacrylic Acid SCHEMBL27869564 0.86 ALDH1A1 (0.45) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL28078237 0.81 TSHR (0.44) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL28300425 0.81 TSHR (0.44) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL11248169 0.79 TSHR (0.47) TSHRCES1CES2ALDH1A1THRB
Methacrylic Acid SCHEMBL7638298 0.79 ALDH1A1 (0.52) TSHRCES1CES2ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107405289-A Cosmetic preparation 大阪有机化学工业株式会社 2017-11-28 CN disclosed
EP-1656116-A2 POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY Vista Scientific LLC (US) 2006-05-17 EP disclosed
WO-2005023181-A2 POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY VISTA SCIENTIFIC (US) 2005-03-17 WO disclosed