Methacrylic Acid

Methacrylic Acid

SCHEMBL28078237

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(CCCC)C(=O)OCC

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
FAAH O00519 2/20 0.39
ALDH1A1 P00352 7/20 0.39
THRB P10828 2/20 0.38
MAPT P10636 2/20 0.37
CES1 P23141 2/20 0.36
GLO1 Q04760 1/20 0.36
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CES2 O00748 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
AKR1B1 P15121 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28300425 1.00 TSHR (0.44) TSHRFAAHALDH1A1THRBMAPT
Methacrylic Acid SCHEMBL11252010 0.93 TSHR (0.50) TSHRFAAHALDH1A1THRBHSD17B10
SCHEMBL196925 0.91 ALDH1A1 (0.45) TSHRFAAHALDH1A1MAPTCES1
Methacrylic Acid SCHEMBL27701943 0.89 TSHR (0.37) TSHRFAAHALDH1A1THRBMAPT
Methacrylic Acid SCHEMBL27706309 0.88 TSHR (0.56) TSHRALDH1A1THRBCES1LMNA
Methacrylic Acid SCHEMBL28098650 0.88 TSHR (0.43) TSHRALDH1A1THRBMAPTCES1
SCHEMBL22122817 0.86 FAAH (0.47) TSHRFAAHALDH1A1THRBHSD17B10
SCHEMBL374969 0.85 FAAH (0.51) TSHRFAAHALDH1A1CES1HSD17B10
SCHEMBL11355650 0.84 TSHR (0.61) TSHRFAAHALDH1A1THRBCES1
SCHEMBL28165834 0.84 ALDH1A1 (0.40) TSHRFAAHALDH1A1MAPTCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103945694-B For the method stably comprising the antibacterial content of the aqueous mineral prepared product of the calcium carbonate grinding natural whiting and/or winnofil and/or dolomite and/or surface reaction 欧米亚国际集团 2016-07-13 CN disclosed