SCHEMBL6061097

SCHEMBL6061097

NC(=O)c1cccc2cc(C=O)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 2/20 0.57
GAA P10253 1/20 0.57
PARP1 P09874 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
PTPN1 P18031 1/20 0.44
KDR P35968 6/20 0.41
AURKA O14965 5/20 0.41
MET P08581 4/20 0.41
TEK Q02763 4/20 0.41
AURKB Q96GD4 4/20 0.41
PDPK1 O15530 1/20 0.40
ABL1 P00519 1/20 0.40
LCK P06239 1/20 0.40
LYN P07948 1/20 0.40
UNG P13051 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196013 0.85 PTPN1 (0.62) KDM4EALDH1A1KMT2AMEN1HPGD
SCHEMBL344963 0.80 ALDH1A1 (0.48) KDM4EALDH1A1GAASMN1; SMN2KMT2A
SCHEMBL634882 0.79 KDM4E (0.65) KDM4EALDH1A1GAAPARP1PTPN1
SCHEMBL29463701 0.77 ALDH1A1 (0.62) KDM4EALDH1A1GAAPARP1HPGD
SCHEMBL6384957 0.77 ALDH1A1 (0.62) KDM4EALDH1A1GAAPARP1HPGD
SCHEMBL1807858 0.77 KDM4E (0.62) KDM4EALDH1A1GAAPARP1SMN1; SMN2
SCHEMBL1807859 0.77 KDM4E (0.62) KDM4EALDH1A1GAAPARP1SMN1; SMN2
SCHEMBL14937023 0.76 ALDH1A1 (0.61) KDM4EALDH1A1GAAPARP1SMN1; SMN2
SCHEMBL10274480 0.76 KDM4E (0.61) KDM4EALDH1A1GAAPARP1KMT2A
SCHEMBL9098185 0.75 PLAU (0.53) KDM4EALDH1A1HPGDUNGCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228132-B1 ACID DYEABLE POLYESTER COMPOSITIONS INVISTA TECH SARL (US) 2006-05-03 EP disclosed
CN-1249141-C Acid dyeable polyester composition DU PONT (CH) 2006-04-05 CN disclosed
CN-1433446-A Acid dyeable pdyester compositions DU PONT (US) 2003-07-30 CN disclosed
EP-1228132-A2 ACID DYEABLE POLYESTER COMPOSITIONS E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 2002-08-07 EP disclosed
WO-2001034693-A3 ACID DYEABLE POLYESTER COMPOSITIONS DU PONT (US) 2001-11-22 WO disclosed
WO-2001034693-A2 ACID DYEABLE POLYESTER COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-05-17 WO disclosed