SCHEMBL7196013

SCHEMBL7196013

O=Cc1ccc2c(C(=O)O)cccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.62
NR4A1 P22736 1/20 0.56
NR4A2 P43354 1/20 0.56
NR4A3 Q92570 1/20 0.56
UNG P13051 1/20 0.49
CDC25B P30305 3/20 0.46
GRIN2D O15399 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
HCAR2 Q8TDS4 1/20 0.44
TBXAS1 P24557 1/20 0.44
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
HSD17B10 Q99714 3/20 0.42
ALDH1A1 P00352 4/20 0.41
SOS1 Q07889 1/20 0.41
NPC1 O15118 1/20 0.41
CYP2C9 P11712 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6061097 0.85 KDM4E (0.57) PTPN1NR4A1NR4A2NR4A3UNG
SCHEMBL344963 0.81 ALDH1A1 (0.48) PTPN1HSD17B10ALDH1A1CYP2C9RAB9A
SCHEMBL8389680 0.81 NR4A1 (0.53) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL28607053 0.78 ALDH1A1 (0.42) PTPN1UNGHCAR2TRIM24TRIM33
Formic Acid SCHEMBL10901133 0.78 PTPN1 (0.60) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL29600450 0.77 NR4A1 (0.68) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL71960 0.77 NR4A1 (0.68) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL22228081 0.77 MEN1 (0.68) NR4A1NR4A2NR4A3UNGCDC25B
SCHEMBL70015 0.77 PTPN1 (1.00) PTPN1NR4A1NR4A2NR4A3CDC25B
SCHEMBL273841 0.77 PTPN1 (0.68) PTPN1NR4A1NR4A2NR4A3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642407-B2 Esterifying the crude aryldicarboxylic acid with an alcohol, removing volatile impurities from the esterification effluent by distillation and separating the aryldicarboxylic acid ester from said effluent EXXON MOBIL CHEMICAL PATENTS INC. 2003-11-04 US claimed
WO-2002094757-A1 PRODUCTION, PURIFICATION AND POLYMERIZATION OF DICARBOXYLIC ACIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-11-28 WO claimed
US-20020173674-A1 Production, purification and polymerization of aromatic dicarboxylic acids EXXONMOBIL CHEMICAL PATENTS, INC. 2002-11-21 US claimed
US-20020173673-A1 Production, purification and polymerization of aromatic dicarboxylic acids EXXONMOBIL CHEMICAL PATENTS, INC. 2002-11-21 US claimed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP claimed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US claimed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP claimed
EP-0735019-B1 Retroviral protease inhibitors MONSANTO CO (US) 2000-09-20 EP disclosed
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed