Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353627 | 1.00 | LMNA (0.32) | LMNAAPLNRUGT2B7 | |
| SCHEMBL11299817 | 1.00 | LMNA (0.32) | LMNAAPLNRUGT2B7 | |
| SCHEMBL16802920 | 0.81 | LMNA (0.36) | LMNA | |
| SCHEMBL3658711 | 0.80 | LMNA (0.30) | LMNA | |
| SCHEMBL3649532 | 0.80 | LMNA (0.30) | LMNA | |
| SCHEMBL9442649 | 0.80 | LMNA (0.30) | LMNA | |
| SCHEMBL3649529 | 0.80 | LMNA (0.30) | LMNA | |
| SCHEMBL9975855 | 0.79 | HPGD (0.33) | LMNA | |
| SCHEMBL14210555 | 0.79 | HPGD (0.33) | LMNA | |
| SCHEMBL3247829 | 0.78 | LMNA (0.33) | LMNAAPLNRUGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102070439-A | Method for preparing (+/-)-2,2-dimethyl-3-vinylcyclopropanecarboxylic acid | UNIV ZHEJIANG | 2011-05-25 | — | — | CN | claimed |
| EP-0194919-B1 | ESTER DERIVATIVES OF 2,2-DIMETHYL-3-ETHENYLCYCLOPROPANE-CARBOXYLIC ACID, THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1990-07-18 | — | — | EP | claimed |
| EP-0194919-A1 | Ester derivatives of 2,2-dimethyl-3-ethenylcyclopropane-carboxylic acid, their preparation, their use as parasiticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1986-09-17 | — | — | EP | claimed |
| EP-0056154-B1 | PROCESS FOR THE PREPARATION OF 2,2-DIMETHYL-3-VINYL-CYCLOPROPANE-CARBOXYLIC ACIDS AND THEIR ESTERS | BAYER AG (DE) | 1984-05-23 | — | — | EP | claimed |
| US-4423243-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| US-8530669-B2 | Ester compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8507692-B2 | Ester compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8440853-B2 | Ester compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20120322869-A1 | ESTER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120322870-A1 | ESTER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120309803-A1 | ESTER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-06 | — | — | US | disclosed |
| US-20120309802-A1 | ESTER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-06 | — | — | US | disclosed |
| EP-0056154-A1 | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropane-carboxylic acids and their esters | BAYER AG (DE) | 1982-07-21 | — | — | EP | disclosed |
| US-4263463-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4256907-A | Preparation of substituted vinylcyclopropane-carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4182906-A | BORON HALIDE CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4118505-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-10-03 | — | — | US | disclosed |
| US-4003945-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-18 | — | — | US | disclosed |
| US-3989750-A | LEWIS ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-02 | — | — | US | disclosed |
| US-3969393-A | Process for preparing cyclopropane-carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322870-A1 | ESTER COMPOUND AND USE THEREOF | C9, CASP4, C1S | LMNA 2337/4885APLNR 4231/4885UGT2B7 2734/4885 |
| US-20120322869-A1 | ESTER COMPOUND AND USE THEREOF | CYP51A1, CTRL, C9 | LMNA 1325/4885APLNR 3467/4885UGT2B7 3230/4885 |
| US-20120309803-A1 | ESTER COMPOUND AND USE THEREOF | CYP51A1, CYP4A11, CES1 | LMNA 1860/4885APLNR 4386/4885UGT2B7 2169/4885 |
| US-20120309802-A1 | ESTER COMPOUND AND USE THEREOF | CYP51A1, CYP4A11, CES1 | LMNA 1860/4885APLNR 4386/4885UGT2B7 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.