Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061731 | 1.00 | MAPT (0.49) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL6062734 | 0.86 | MAPT (0.47) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL6062729 | 0.86 | MAPT (0.47) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL14498297 | 0.77 | MAPT (0.43) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL14498299 | 0.77 | NR1H4 (0.58) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6061638 | 0.77 | NR1H4 (0.58) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1100400 | 0.76 | AKR1C3 (0.60) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL1100398 | 0.76 | AKR1C3 (0.60) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL872233 | 0.73 | MAPT (0.59) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL13860473 | 0.71 | MAPT (0.55) | MAPTLMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687250-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | Takasago International Corporation (JP) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051882-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-09 | — | — | WO | disclosed |