Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.52 |
| ▸ | LOX | P28300 | 1/20 | 0.52 |
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658888 | 0.98 | LOXL2 (0.53) | LOXL2LOXNNMTMAOBKDM1A | |
| SCHEMBL1146238 | 0.98 | LOXL2 (0.53) | LOXL2LOXNNMTMAOBKDM1A | |
| SCHEMBL5547238 | 0.98 | LOXL2 (0.53) | LOXL2LOXNNMTMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL5013392 | 0.96 | LOXL2 (0.52) | LOXL2LOXNNMTMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL6234391 | 0.96 | LOXL2 (0.52) | LOXL2LOXNNMTMAOBKDM1A | |
| SCHEMBL5013531 | 0.86 | NNMT (0.46) | LOXL2LOXNNMTKLKB1MKNK1 | |
| SCHEMBL31666977 | 0.82 | TAAR1 (0.52) | LOXL2LOXNNMTMAOBKDM1A | |
| SCHEMBL1967473 | 0.82 | TAAR1 (0.52) | LOXL2LOXNNMTMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL5688361 | 0.81 | TAAR1 (0.50) | LOXL2LOXNNMTMAOBKDM1A | |
| SCHEMBL20771833 | 0.80 | MAOB (0.51) | LOXL2LOXMAOBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720856-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005077050-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |