SCHEMBL6062147

SCHEMBL6062147

COC1=CC[CH]C(c2ccc(Br)cc2)=C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.31
CSNK2A1 P68400 1/20 0.31
AURKB Q96GD4 1/20 0.31
MAP4K5 Q9Y4K4 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31
TUBA1C Q9BQE3 1/20 0.31
TUBB6 Q9BUF5 1/20 0.31
TUBB2B Q9BVA1 1/20 0.31
TUBB1 Q9H4B7 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4806936 0.84 ACHE (0.35) KMT2ARAB9ANPC1
SCHEMBL4805626 0.84 CA12 (0.41) IDO1MEN1KMT2ARAB9AHPGD
SCHEMBL4807843 0.82 MEN1 (0.33) MEN1KMT2ARAB9AHPGDMAPK1
SCHEMBL4802145 0.75 AHR (0.41)
SCHEMBL4015171 0.72
SCHEMBL4801089 0.70 NOTUM (0.40) MAPTNPC1HTR2C
SCHEMBL9533711 0.69 HPGD (0.44) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL2464091 0.66
SCHEMBL7862431 0.65
SCHEMBL4742508 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675813-A1 METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES Applied Research Systems ARS Holding N.V. (NL) 2006-07-05 EP disclosed
WO-2005037758-A1 METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) 2005-04-28 WO disclosed