Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805626 | 0.76 | CA12 (0.41) | HPGDALDH1A1TDP1MEN1TP53 | |
| SCHEMBL9440408 | 0.70 | HPGD (0.54) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| SCHEMBL9440328 | 0.69 | HPGD (0.53) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| SCHEMBL508167 | 0.69 | HPGD (0.53) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| SCHEMBL8503886 | 0.69 | HPGD (0.52) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| SCHEMBL6062147 | 0.69 | PIM1 (0.31) | HPGDALDH1A1TDP1MEN1MAPT | |
| SCHEMBL4807843 | 0.69 | MEN1 (0.33) | HPGDMEN1TP53CYP1A2ALOX15 | |
| SCHEMBL1299701 | 0.68 | HPGD (0.63) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL507244 | 0.68 | HPGD (0.52) | HPGDPARP1ALDH1A1TDP1MEN1 | |
| SCHEMBL27898008 | 0.68 | CA12 (0.46) | HPGDPARP1ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | claimed |