SCHEMBL6062736

SCHEMBL6062736

C=CCCC([SiH3])(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063912 0.87 TSHR (0.41) TSHRALDH1A1
SCHEMBL340733 0.76
SCHEMBL6063939 0.76 TSHR (0.33) TSHRALDH1A1
SCHEMBL2326075 0.76 TSHR (0.39) TSHRALDH1A1
SCHEMBL6063700 0.76 NR1I2 (0.31)
SCHEMBL537895 0.72
SCHEMBL17675053 0.69
SCHEMBL21332490 0.69 LMNA (0.30) TSHR
SCHEMBL1847271 0.69
SCHEMBL1003396 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022230944-A1 PLANARIZING FILM MANUFACTURING METHOD, PLANARIZING FILM MATERIAL, AND PLANARIZING FILM 東ソー株式会社 2022-11-03 WO disclosed
US-9994681-B2 Organopolysiloxane prepolymer and a curable organopolysiloxane composition comprising the same HENKEL AG & CO. KGAA (DE) 2018-06-12 US disclosed
EP-3245256-A1 ORGANOPOLYSILOXANE PREPOLYMER AND CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING SAME Henkel AG & Co. KGaA (DE) 2017-11-22 EP disclosed
US-20170306100-A1 Organopolysiloxane Prepolymer and a Curable Organopolysiloxane Composition Comprising the Same HENKEL CORPORATION 2017-10-26 US disclosed
WO-2016112487-A1 ORGANOPOLYSILOXANE PREPOLYMER AND CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING SAME HENKEL (CHINA) COMPANY LIMITED (CN) 2016-07-21 WO disclosed
WO-2016054781-A1 AN ORGANOPOLYSILOXANE PREPOLYMER AND A CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING THE SAME HENKEL (CHINA) COMPANY LIMITED (CN) 2016-04-14 WO disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed
EP-0653447-B1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-06-06 EP disclosed
US-5457167-A Impact strength, chemical resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-10-10 US disclosed
EP-0653447-A1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-05-17 EP disclosed