SCHEMBL6062845

SCHEMBL6062845

O=C(OCCOCCOCCOC(=O)c1ccccc1Cl)c1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.57
TSHR P16473 5/20 0.55
ALDH1A1 P00352 5/20 0.52
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
ADRB2 P07550 2/20 0.49
ADRB1 P08588 2/20 0.49
ADRB3 P13945 2/20 0.49
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
NPC1 O15118 3/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 2/20 0.48
MEN1 O00255 1/20 0.48
JAK2 O60674 1/20 0.48
S1PR2 O95136 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062054 1.00 HPGD (0.57) HPGDTSHRALDH1A1CES2CES1
SCHEMBL6062063 1.00 HPGD (0.57) HPGDTSHRALDH1A1CES2CES1
SCHEMBL28107072 0.87 ALDH1A1 (0.51) HPGDTSHRALDH1A1TDP1L3MBTL1
SCHEMBL28152534 0.85 HPGD (0.57) HPGDTSHRALDH1A1CES2CES1
Propene SCHEMBL6062593 0.84 TSHR (0.54) HPGDTSHRALDH1A1CES2CES1
Propene SCHEMBL6062307 0.84 TSHR (0.54) HPGDTSHRALDH1A1CES2CES1
Propene SCHEMBL6062176 0.84 TSHR (0.54) HPGDTSHRALDH1A1CES2CES1
SCHEMBL2059610 0.84 ALDH1A1 (0.76) HPGDTSHRALDH1A1ADRB2ADRB1
SCHEMBL32681300 0.84 HPGD (0.56) HPGDTSHRALDH1A1CES2CES1
SCHEMBL21953836 0.83 CES2 (0.52) HPGDTSHRALDH1A1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1454958-B1 LACTIC ACID POLYMER COMPOSITION AND MOLDED OBJECT THEREOF NEW JAPAN CHEM CO LTD (JP) 2006-10-04 EP disclosed
US-20050001349-A1 Lactic acid polymer composition and molded object thereof NEW JAPAN CHEMICAL CO., LTD. (JP) 2005-01-06 US disclosed
EP-1454958-A1 LACTIC ACID POLYMER COMPOSITION AND MOLDED OBJECT THEREOF NEW JAPAN CHEMICAL CO.,LTD. (JP) 2004-09-08 EP disclosed