SCHEMBL6062887

SCHEMBL6062887

CCOC([SiH3])(OCC)C1CC2C=CC1C2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062704 0.79 ALDH1A1 (0.33) ALDH1A1KDM4EUSP2TDP1
SCHEMBL6063112 0.79 ALDH1A1 (0.31) ALDH1A1KDM4EUSP2TDP1
SCHEMBL6062711 0.74 KDM4E (0.41) ALDH1A1KDM4E
SCHEMBL6063249 0.72 ALDH1A1 (0.35) ALDH1A1KDM4EUSP2TDP1
SCHEMBL6064280 0.71 KDM4E (0.40) ALDH1A1KDM4E
SCHEMBL7684510 0.70 ALDH1A1 (0.33) ALDH1A1KDM4EUSP2TDP1
SCHEMBL6064276 0.69 KDM4E (0.38) ALDH1A1KDM4E
SCHEMBL4604155 0.69 ALDH1A1 (0.32) ALDH1A1KDM4EUSP2TDP1
SCHEMBL6062515 0.69 ALDH1A1 (0.33) ALDH1A1KDM4EUSP2TDP1
SCHEMBL9245372 0.68 ALDH1A1 (0.38) ALDH1A1KDM4EUSP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed