SCHEMBL4604155

SCHEMBL4604155

CCO[SiH](OCC)C(C)(Cl)C1CC2C=CC1C2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
USP2 O75604 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603868 0.81 USP2 (0.31) ALDH1A1USP2TDP1
SCHEMBL6062887 0.69 ALDH1A1 (0.34) ALDH1A1USP2TDP1KDM4E
SCHEMBL5930981 0.68 KDM4E (0.37) ALDH1A1KDM4E
SCHEMBL9245372 0.67 ALDH1A1 (0.38) ALDH1A1USP2TDP1KDM4E
SCHEMBL295008 0.67 KDM4E (0.39) ALDH1A1KDM4E
SCHEMBL4602458 0.66 ALDH1A1 (0.38) ALDH1A1USP2TDP1KDM4E
SCHEMBL27661449 0.66 KDM4E (0.38) ALDH1A1KDM4E
SCHEMBL21626124 0.65 ALDH1A1 (0.42) ALDH1A1USP2TDP1KDM4E
SCHEMBL6063727 0.65 USP2 (0.33) ALDH1A1USP2TDP1
SCHEMBL3277483 0.65 KDM4E (0.44) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed