Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064310 | 0.89 | GBA1 (0.41) | GBA1FAAHNAAAABL1RIN1 | |
| SCHEMBL20733168 | 0.83 | GBA1 (0.44) | GBA1FAAHNAAAPOLBMAPT | |
| SCHEMBL3636070 | 0.73 | MEN1 (0.43) | GBA1POLBMAPTNPSR1ABL1 | |
| SCHEMBL8394535 | 0.72 | GBA1 (0.43) | GBA1NAAAPOLBMAPTNPSR1 | |
| SCHEMBL10337442 | 0.72 | GBA1 (0.43) | GBA1NAAAPOLBMAPTNPSR1 | |
| SCHEMBL20733170 | 0.71 | GBA1 (0.45) | GBA1FAAHNAAAPOLBMAPT | |
| SCHEMBL7143296 | 0.71 | — | — | |
| SCHEMBL27904162 | 0.69 | PTGER4 (0.47) | POLBABL1RIN1TDP1TP53 | |
| SCHEMBL8392269 | 0.69 | MEN1 (0.42) | GBA1NAAATDP1 | |
| SCHEMBL18640661 | 0.68 | GBA1 (0.41) | GBA1FAAHPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694748-A1 | METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY | 3M Innovative Properties Company (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005047373-A1 | METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-26 | — | — | WO | disclosed |