Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA9 | Q16790 | 9/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA5A | P35218 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266011 | 0.77 | PTGES2 (0.48) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4662839 | 0.77 | PTGES2 (0.48) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4661687 | 0.77 | PTGES2 (0.48) | CA2CA1CA9CA12CA6 | |
| SCHEMBL8679535 | 0.77 | CA2 (0.44) | CA2CA1CA9CA12CA6 | |
| SCHEMBL253349 | 0.76 | CA2 (0.42) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL3517767 | 0.76 | PTGES2 (0.47) | CA2CA1CA9CA12CA6 | |
| SCHEMBL7265161 | 0.75 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL9242437 | 0.74 | KDM4E (0.47) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL15106836 | 0.73 | IDO1 (0.46) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL10762626 | 0.73 | GABRA1 (0.43) | KDM4EMAPTCYP3A4ALOX15CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687265-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051898-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |