Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.36 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.36 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.36 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063049 | 0.88 | ALOX15 (0.47) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL6063384 | 0.83 | ALOX15 (0.43) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL6063686 | 0.80 | ALOX15 (0.49) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL27846924 | 0.79 | L3MBTL1 (0.54) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL13342736 | 0.76 | GAA (0.57) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL249930 | 0.75 | TYR (0.54) | — | |
| SCHEMBL15557997 | 0.75 | ALOX15 (0.59) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL6063596 | 0.74 | ALOX15 (0.44) | ALOX15KMT2AKDM4ESMN1; SMN2GAA | |
| SCHEMBL6063578 | 0.74 | KMT2A (0.50) | ALOX15KMT2AMEN1KDM4ERECQL | |
| SCHEMBL7911474 | 0.72 | ALOX15 (0.53) | ALOX15KMT2AMEN1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680397-A2 | NOVEL COMPOUNDS AND THEIR USE AS ANTIDIABETIC AND HYPOLIPIDEMIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005040102-A2 | NOVEL COMPOUNDS AND THEIR USE AS ANTIDIABETIC AND HYPOLIPIDEMIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-05-06 | — | — | WO | disclosed |