Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063926 | 0.88 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL6064197 | 0.78 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL23132563 | 0.76 | TSHR (0.44) | TSHRALDH1A1THRBGGPS1FDPS | |
| SCHEMBL4791142 | 0.76 | TSHR (0.44) | TSHRALDH1A1THRBGGPS1FDPS | |
| SCHEMBL7752834 | 0.75 | TSHR (0.41) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL8687202 | 0.75 | TSHR (0.50) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL17351709 | 0.75 | TSHR (0.50) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL10416462 | 0.75 | TSHR (0.50) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL10797646 | 0.75 | TSHR (0.50) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL3774446 | 0.74 | TSHR (0.42) | TSHRALDH1A1THRBGGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963996-B9 | Transition metal compound, catalyst component and catalyst for olefin polymerization and process for the preparation of alpha-olefin polymer | JAPAN POLYCHEM CORP (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-0963996-B1 | Transition metal compound, catalyst component and catalyst for olefin polymerization and process for the preparation of alpha-olefin polymer | JAPAN POLYCHEM CORP (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-6218558-B1 | BRIDGED OXYGEN-, NITROGEN- OR SULFUR-CONTAINING METALLOCENE CATALYST CONTAINING AT LEAST CYCLOPENTADIENE RING FUSED TO A C7-10 RING | JAPAN POLYCHEM CORPORATION (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0963996-A2 | Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer | Japan Polychem Corporation (JP) | 1999-12-15 | — | — | EP | disclosed |