SCHEMBL6063405

SCHEMBL6063405

CN(C(=O)CC[C@H](N)C(=O)O)[C@@H](C[SeH])C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 3/20 0.46
SLC1A2 P43004 3/20 0.46
SLC1A1 P43005 3/20 0.46
GRIK1 P39086 2/20 0.46
GRIK2 Q13002 2/20 0.46
GSR P00390 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK3 Q13003 1/20 0.46
GRIN2B Q13224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23716475 1.00 SLC1A3 (0.46) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL6062374 0.89 GLO1 (0.39) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL22360987 0.89 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL17079901 0.83 GRIK1 (0.46) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL18030268 0.83 GRM8 (0.60) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL9085219 0.83 GRM8 (0.60) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL9086732 0.83 GRIK1 (0.50) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL23716476 0.83 GRIK1 (0.46) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL9086724 0.83 GRIK1 (0.50) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL9085224 0.83 GRM8 (0.60) SLC1A3SLC1A2SLC1A1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060198906-A1 Compositions and Method to Increase Serum Levels of HDL cholesterol and Lower the Risk of Cardiovascular Disease SAMI LABS LIMITED (IN) 2006-09-07 US claimed
CN-117981749-A Construction of amphiphilic polysaccharide-based nano-selenium delivery system 海南大学 2024-05-07 CN disclosed
CN-114984038-A Selenium-containing composition and its use for treating and preventing diseases or disorders associated with mitochondrial dysfunction 全技术公司 2022-09-02 CN disclosed
CN-114533753-A Selenium-containing composition and application thereof in treating and preventing diseases or symptoms related to mitochondrial dysfunction 全技术公司 2022-05-27 CN disclosed
CN-113694074-A Compositions of selenium organic compounds and methods of use thereof 全技术公司 2021-11-26 CN disclosed
CN-113694074-A Compositions of selenium organic compounds and methods of use thereof 全技术公司 2021-11-26 CN disclosed
CN-106822168-B Compositions of selenium-containing organic compounds and methods of use thereof 全技术公司 2020-11-27 CN disclosed
CN-106822168-B Compositions of selenium-containing organic compounds and methods of use thereof 全技术公司 2020-11-27 CN disclosed
US-10201558-B2 Compositions of selenoorganic compounds and methods of use thereof ALLTECH, INC. (US) 2019-02-12 US disclosed
EP-3144001-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF Alltech, Inc. (US) 2017-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10201558-B2 Compositions of selenoorganic compounds and methods of use thereof PSEN2, PSEN1, BACE1 SLC1A3 1613/4885SLC1A2 1229/4885SLC1A1 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.