SCHEMBL17079901

SCHEMBL17079901

CN(C(=O)CC[C@H](N)C(=O)O)[C@@H](CS)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.46
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
GRIK2 Q13002 2/20 0.46
GSR P00390 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK3 Q13003 1/20 0.46
GRIN2B Q13224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23716476 1.00 GRIK1 (0.46) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL28335433 0.89 SLC1A1 (0.42) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL17077617 0.89 SLC1A1 (0.42) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL9086724 0.83 GRIK1 (0.50) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL9085219 0.83 GRM8 (0.60) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL9085224 0.83 GRM8 (0.60) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL9086732 0.83 GRIK1 (0.50) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL18030268 0.83 GRM8 (0.60) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL23716475 0.83 SLC1A3 (0.46) GRIK1SLC1A3SLC1A2SLC1A1GRIK2
SCHEMBL6063405 0.83 SLC1A3 (0.46) GRIK1SLC1A3SLC1A2SLC1A1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3144001-B1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH INC (US) 2021-08-11 EP claimed
US-9642874-B2 Compositions of selenoorganic compounds and methods of use thereof ALLTECH, INC. (US) 2017-05-09 US claimed
WO-2017048253-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH, INC. (US) 2017-03-23 WO claimed
EP-3144001-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF Alltech, Inc. (US) 2017-03-22 EP claimed
US-20160082033-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2016-03-24 US claimed
US-20160045533-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2016-02-18 US claimed
EP-3144001-B1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH INC (US) 2021-08-11 EP disclosed
EP-3116511-B1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH INC (US) 2020-08-26 EP disclosed
US-10201559-B2 Compositions of selenoorganic compounds and methods of use thereof ALLTECH, INC. (US) 2019-02-12 US disclosed
US-10201558-B2 Compositions of selenoorganic compounds and methods of use thereof ALLTECH, INC. (US) 2019-02-12 US disclosed
US-9642874-B2 Compositions of selenoorganic compounds and methods of use thereof ALLTECH, INC. (US) 2017-05-09 US disclosed
WO-2017048253-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH, INC. (US) 2017-03-23 WO disclosed
WO-2017048252-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH, INC. (US) 2017-03-23 WO disclosed
EP-3144001-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF Alltech, Inc. (US) 2017-03-22 EP disclosed
EP-3116511-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF Alltech, Inc. (US) 2017-01-18 EP disclosed
US-20160361338-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH, INC. (US) 2016-12-15 US disclosed
US-20160082033-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2016-03-24 US disclosed
US-20160045533-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2016-02-18 US disclosed
WO-2015137983-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF ALLTECH, INC. (US) 2015-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160045533-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF SCLY, BHMT2, CBS GRIK1 1127/4885SLC1A3 350/4885SLC1A2 206/4885
US-10201559-B2 Compositions of selenoorganic compounds and methods of use thereof SHMT2, FPGS, MTR GRIK1 1133/4885SLC1A3 845/4885SLC1A2 606/4885
US-20160361338-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF SHMT2, FPGS, MTR GRIK1 1133/4885SLC1A3 845/4885SLC1A2 606/4885
US-20160082033-A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF PSEN2, PSEN1, BACE1 GRIK1 1668/4885SLC1A3 1613/4885SLC1A2 1229/4885
US-10201558-B2 Compositions of selenoorganic compounds and methods of use thereof PSEN2, PSEN1, BACE1 GRIK1 1668/4885SLC1A3 1613/4885SLC1A2 1229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.