SCHEMBL6063543

SCHEMBL6063543

Cc1c(F)cc(F)cc1Bc1c(F)cc(F)cc1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351796 0.89 RAPGEF4 (0.34) RAPGEF4
SCHEMBL5345179 0.88
SCHEMBL5351133 0.88 TAAR1 (0.36)
SCHEMBL6051855 0.87
SCHEMBL6063371 0.87
SCHEMBL6062127 0.86 CES2 (0.31)
SCHEMBL5352273 0.86
SCHEMBL5351779 0.85 RAPGEF4 (0.30) RAPGEF4
SCHEMBL5350586 0.84 TUBB1 (0.31)
SCHEMBL6063044 0.81 CES2 (0.33) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed