SCHEMBL6064149

SCHEMBL6064149

C=CCCCCCCCCCC[SiH2]C(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 3/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
ABCC4 O15439 1/20 0.32
HPGD P15428 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064125 1.00 TSHR (0.41) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL31601052 1.00 TSHR (0.41) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL5410125 1.00 TSHR (0.41) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL6062876 0.98 TSHR (0.38) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL6063306 0.92 TSHR (0.37) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6063973 0.83 TSHR (0.32) TSHR
SCHEMBL1920971 0.82
SCHEMBL704741 0.80
SCHEMBL9622182 0.76
SCHEMBL646422 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed