Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851728 | 0.89 | CCKBR (0.40) | BCHECCKBRHRH2OPRM1HTR2B | |
| SCHEMBL31366241 | 0.83 | CCKBR (0.39) | BCHECCKBROPRM1HDAC6PAX8 | |
| SCHEMBL14610590 | 0.83 | CCKBR (0.39) | BCHECCKBROPRM1HDAC6PAX8 | |
| SCHEMBL7074697 | 0.83 | BCHE (0.48) | BCHECCKBR | |
| SCHEMBL19149276 | 0.83 | HTR2A (0.45) | BCHECCKBRAKT1 | |
| SCHEMBL5539765 | 0.83 | CCKBR (0.39) | BCHECCKBRHRH2OPRM1HTR2B | |
| SCHEMBL28191402 | 0.82 | CCKBR (0.45) | BCHECCKBRHRH2OPRM1HTR2B | |
| SCHEMBL8523648 | 0.81 | BCHE (0.47) | BCHECCKBR | |
| SCHEMBL5546413 | 0.81 | CCKBR (0.38) | BCHECCKBRHRH2OPRM1HTR2B | |
| SCHEMBL22582292 | 0.80 | BCHE (0.46) | BCHECCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680397-A2 | NOVEL COMPOUNDS AND THEIR USE AS ANTIDIABETIC AND HYPOLIPIDEMIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005040102-A2 | NOVEL COMPOUNDS AND THEIR USE AS ANTIDIABETIC AND HYPOLIPIDEMIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-05-06 | — | — | WO | disclosed |