Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756698 | 0.98 | BCHE (0.46) | BCHECCKBRCYSLTR2CYSLTR1 | |
| SCHEMBL22582292 | 0.98 | BCHE (0.46) | BCHECCKBRCYSLTR2CYSLTR1 | |
| SCHEMBL7074697 | 0.95 | BCHE (0.48) | BCHECCKBRHTR5A | |
| SCHEMBL8261364 | 0.88 | HTR5A (0.41) | BCHECCKBRHTR5A | |
| SCHEMBL1325640 | 0.85 | SIGMAR1 (0.42) | BCHECCKBR | |
| SCHEMBL7692638 | 0.84 | BCHE (0.64) | BCHECYSLTR2CYSLTR1HTR5A | |
| Dimethylamine SCHEMBL8649623 | 0.83 | BCHE (0.39) | BCHECCKBRHTR5A | |
| SCHEMBL5546413 | 0.83 | CCKBR (0.38) | BCHECCKBR | |
| SCHEMBL20879359 | 0.82 | BCHE (0.37) | BCHECCKBR | |
| SCHEMBL5542142 | 0.82 | CCKBR (0.37) | BCHECCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0810214-A4 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025396-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1996-08-22 | — | — | WO | disclosed |
| US-4153789-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-05-08 | — | — | US | disclosed |
| US-4080330-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1978-03-21 | — | — | US | disclosed |