SCHEMBL6064281

SCHEMBL6064281

CCO[Si](C)(CCC1CC2C=CC1C2)OCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063180 0.87 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL200331 0.85 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064256 0.83 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064034 0.83 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4602399 0.83 ALDH1A1 (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064264 0.83 ALDH1A1 (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064427 0.83 ALDH1A1 (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15802770 0.82 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL5701743 0.82 ALDH1A1 (0.37) KDM4EALDH1A1MEN1KMT2A
SCHEMBL6063034 0.81 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160145400-A1 BLOCK COPOLYMERS IN LAMINATE MANUFACTURING INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-05-26 US disclosed
US-8742155-B2 Preparation of organoxysilyl or siloxy-containing ethylnorbornene compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-03 US disclosed
CN-102993227-A Preparation of organoxysilyl or siloxy-containing ethylnorbornene compound SHINETSU CHEMICAL CO 2013-03-27 CN disclosed
US-20130066095-A1 PREPARATION OF ORGANOXYSILYL OR SILOXY-CONTAINING ETHYLNORBORNENE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-03-14 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066095-A1 PREPARATION OF ORGANOXYSILYL OR SILOXY-CONTAINING ETHYLNORBORNENE COMPOUND SIK2, RNF168, OR51E2 KDM4E 3559/4885ALDH1A1 4087/4885MEN1 929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.