Ether

Ether

SCHEMBL6064358

CCC(C)(Br)C(=O)O.CCOCC

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.32
TSHR P16473 3/20 0.32
ADORA3 P0DMS8 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
POLB P06746 1/20 0.30
TRPA1 O75762 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1732520 0.88
SCHEMBL287909 0.88
SCHEMBL1732575 0.88
SCHEMBL3142027 0.82 ALDH1A1 (0.38) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL30955711 0.79 PIN1 (0.39) ALDH1A1TSHRCYP2C19TRPA1CYP4F2
Pivalate SCHEMBL11039116 0.78 ALDH1A1 (0.40) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL30688676 0.77 KCNN4 (0.34) ALDH1A1TSHRPOLB
Benzene SCHEMBL11528901 0.75 ALDH1A1 (0.46) ALDH1A1TSHRPOLB
Ether SCHEMBL5665509 0.74 TET2 (0.40) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
Ether SCHEMBL115545 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006046933-A1 SEDATIVE AND SPASMOLYTIC MEDICINAL AGENT AND METHOD FOR THE PRODUCTION THEREOF (VARIANTS) RYBCHUK VIKTOR OLEXANDROVYCH (UA) 2006-05-04 WO disclosed