Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.66 |
| ▸ | ALPG | P10696 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819091 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8807762 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL31282379 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2183416 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9367076 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL69332 | 0.85 | MCL1 (0.63) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8808189 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8809073 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL15842381 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4271081 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110934864-A | Application of 4-methyl-6, 7-dimethoxycoumarin in preparing medicine for preventing and treating diabetic nephropathy | 佛山科学技术学院 | 2020-03-31 | — | — | CN | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| US-8410110-B2 | 9-(piperazinylalkyl) carbazoles as Bax-modulators | MERCK SERONO SA (CH) | 2013-04-02 | — | — | US | claimed |
| US-20120040933-A1 | 9-(PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2012-02-16 | — | — | US | claimed |
| US-8053436-B1 | 9-(piperazinylalkyl) carbazoles as bax-modulators | MERCK SERONO SA (CH) | 2011-11-08 | — | — | US | claimed |
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |
| EP-1237887-A1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-11 | — | — | EP | claimed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | claimed |
| US-5663029-A | DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-3674381-B1 | ORGANIC OPTICAL MATERIAL | JAPAN SCIENCE & TECH AGENCY (JP) | 2023-05-10 | — | — | EP | disclosed |
| CN-113975270-A | New application of coumarin | 广州康臣药业有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113917009-A | Construction method and application of bupleurum chinense non-saponin component HPLC fingerprint | 山西大学 | 2022-01-11 | — | — | CN | disclosed |
| US-20200284946-A1 | ORGANIC OPTICAL MATERIAL | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-09-10 | — | — | US | disclosed |
| US-20200284946-A1 | ORGANIC OPTICAL MATERIAL | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-09-10 | — | — | US | disclosed |
| WO-2010078333-A2 | BENZOXAZOLE-BASED FLUORESCENT METAL ION INDICATORS | Life Technologies Corporation (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100028469-A1 | Extracts of Cranberry and Methods of Using Thereof | HERBALSCIENCE GROUP, LLC (US) | 2010-02-04 | — | — | US | disclosed |
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | disclosed |
| EP-1237887-A1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200284946-A1 | ORGANIC OPTICAL MATERIAL | SLC43A1, SLCO4C1, SLCO1A2 | KDM4E 3282/4885ALDH1A1 693/4885HPGD 4073/4885 |
| US-20120040933-A1 | 9-(PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | BCL2, BAX, BAD | KDM4E 1555/4885ALDH1A1 2766/4885HPGD 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.