SCHEMBL6064488

SCHEMBL6064488

CCCO[Si](CCCOCC1CO1)(OC)OCC

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064397 0.96 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064602 0.96 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1360905 0.94 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064005 0.93 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064312 0.93 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6063414 0.93 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6063435 0.92 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL283698 0.91 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1920460 0.90 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6063082 0.90 TSHR (0.55) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7141306-B1 Sol-gel composition and process for coating aerospace alloys CESSNA AIRCRAFT COMPANY (US) 2006-11-28 US disclosed